The Efficacy of Piroxicam/lidocaine/cyclobenzaprine Hydrochloride Topical Gel in the Pain Management during Extracorporeal Shock Wave Lithotripsy (eswl)

The aim of the study was to evaluate the efficacy of the combination for cutaneous application of piroxicam/lidocaine/cyclobenzaprine hydrochloride for the pain management during Extracorporeal Shock Wave Lithotripsy (ESWL). A number of 256 patients with renal and ureteral stones were randomly assigned to one of the 3 groups: group A (topical analgesic 30 minutes prior to ESWL), group B (topical analgesic 60 minutes prior to ESWL) and group C (no treatment prior the ESWL). The pain before and during the procedure was evaluated with a Visual Analogue Scale (VAS) and for each patient the rescue analgesic medication was quantified. Regarding age, weight, stone size, number of shock wave delivered and maximum voltage used, no statistical differences were noticed in the three groups (p > 0.05). The topical application of a gel with this analgetic combination before the ESWL provided significant relief of the pain during this procedure in comparison with no treatment. The topical analgesic before lithotripsy also reduced the need of rescue medication. The gel with piroxicam/lidocaine/cyclobenzaprine hydrochloride is a valuable alternative for the management of pain during ESWL.